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. Author manuscript; available in PMC: 2023 Jun 1.
Published in final edited form as: Trends Neurosci. 2022 Apr 13;45(6):483–498. doi: 10.1016/j.tins.2022.03.004

Figure 2. Examples of paracrine signaling by soluble ectodomains shed from synaptic proteins.

Figure 2.

Proteins of origin, sheddases, regulation of shedding, soluble ectodomains, protein targets and biological actions are indicated for the ES of NRXN1 [10] (A), CNTNAP2 [20] (B), NLGN1 [67] (C) and SIRPα [70] (D).