Table 1.

Mendelian randomization estimates for the relationship between genetically instrumented periodontitis and psoriasis and vice versa

Outcome	Exposure	Method	OR	(95% CI)	P value
psoriasis	periodontitis	Inverse variance weighted	1.017	(0.95–1.088)	0.6247
		Weighted median	1.020	(0.926–1.123)	0.6868
		Robust adjusted profile score	1.019	(0.947–1.098)	0.6098
		IVW radial	1.017	(0.956–1.082)	0.5918
		MR-PRESSO	1.017	(0.956–1.082)	0.5935
periodontitis	psoriasis	Inverse variance weighted	0.995	(0.967–1.023)	0.7070
		Weighted median	1.000	(0.959–1.044)	0.9837
		Robust adjusted profile score	0.995	(0.965–1.026)	0.7471
		IVW radial	0.995	(0.967–1.023)	0.7014
		MR-PRESSO	0.995	(0.967–1.023)	0.7033

IVW, inverse variance weighted; OR, odds ratio; CI, confidence interval; MR-PRESSO, MR Pleiotropy RESidual Sum and Outlier.