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. Author manuscript; available in PMC: 2023 Jun 1.
Published in final edited form as: Alcohol. 2022 Feb 26;101:17–26. doi: 10.1016/j.alcohol.2022.02.003

Figure 5. Potentiated excitatory drive onto PFC PV-INs emerges during abstinence.

Figure 5.

(a) A positive correlation was observed between the length of time elapsed since the last ethanol reward pairing and PV-IN sEPSC amplitude. The relationship was detected in all mice and in female mice (light red fill) and male mice (dark red fill) when separated. The error lines and fill denote the 95% confidence interval for each best-fit line. (b) No relationship between sEPSC amplitude and the length of time elapsed since the last ethanol aversion pairing. (c) No relationship between sEPSC frequency and the length of time elapsed since the last ethanol reward pairing. (d) No relationship between sEPSC frequency and the length of time elapsed since the last ethanol aversion pairing. n/N = 8-14 cells from 3-5 mice per group.