Table 4.

UVA and MVA of CO Associated with Baseline Basophils and BLR in mHSPC.

	UVA				MVA†
	OS		PFS		OS		PFS
	HR (CI‡)	p-value	HR (CI‡)	p-value	HR (CI‡)	p-value	HR (CI‡)	p-value
Basophils ≥ 0.1 (Above) vs. <0.1 (Below optimal cut)	3.69 (1.91–7.12)	<0.001	2.39 (1.42–4.01)	0.001	3.51 (1.65–7.43)	0.001	1.88 (1.05–3.38)	0.034
BLR ≥ 0.0142 (Above) vs. < 0.0142 (Below optimal cut)	1.35 (0.73–2.50)	0.338	0.76 (0.51–1.14)	0.187	2.11 (1.09–4.10)	0.028	0.87 (0.55–1.35)	0.526

^†The MVA was built in Cox proportional hazard model by controlling for drug, race, age at diagnosis, disease volume, ECOG, and Gleason.

^‡95% confidence interval

BLR = basophil-to-lymphocyte ratio