TABLE 2.
Clinical Characteristic | IPD DBS (n = 14) | LRRK2 DBS (n = 9) | p Value |
---|---|---|---|
Male | 13/14 (92.86) | 7/9 (77.78) | 0.53 |
Age at PD motor symptom onset, yrs | 52.33 ± 9.01 | 50.11 ± 13.56 | 0.72 |
Age at PD diagnosis, yrs | 53.00 ± 9.12 | 51.11 ± 12.83 | 0.72 |
Site of onset | |||
Arm | 7/14 (50.00) | 3/9 (33.3) | 0.39 |
Leg | 4/14 (28.57) | 3/9 (33.3) | >0.99 |
Gait | 1/14 (7.14) | 3/9 (33.3) | 0.27 |
Duration of disease at diagnosis, yrs | 0.67 ± 0.72 | 1.67 ± 1.22 | 0.03 |
Disease duration at levodopa institution, yrs | 2.69 ± 1.93 | 6.25 ± 6.80 | 0.14 |
Age at surgery, yrs | 64.1 ± 6.33 | 63.11 ± 15.09 | 0.97 |
Duration of disease (diagnosis) at surgery, yrs | 10.59 ± 6.68 | 11.11 ± 5.13 | 0.52 |
Duration of disease (symptoms) at surgery, yrs | 10.53 ± 6.27 | 12.78 ± 4.38 | 0.22 |
Median LEDD at surgery (IQR) | 938 (498.5) | 1228 (491) | 0.09 |
Median UPDRS-III score at surgery (IQR) | 9 (11) | 16 (21) | 0.13 |
Data given as mean ± SD or number (%), unless otherwise indicated.