Table 1.
Sample descriptives for total sample (n = 1789) of individuals with a 22q11.2 deletion, baseline subset (n = 657) and longitudinal subset (n = 708).
| Total sample | Subset: baseline | Subset: longitudinal | p a | |
|---|---|---|---|---|
| N = 1789 | N = 657 | N = 708 | ||
| Age in years at first assessment | – | |||
| Mean (SD) | 17.1 (8.0) | 11.6 (4.8) | ||
| Median (Range) | 15.0 (6.0–37.8) | 10.4 (6.0–35.2) | <0.001 | |
| Age in years at last assessment | – | – | ||
| Mean (SD) | 17.9 (5.8) | |||
| Median (Range) | 17.1 (7.4–38) | – | ||
| Sex (% males) | 868 (48.5%) | 313 (47.6%) | 354 (50%) | 0.4139 |
| Psychotic illness expression | <0.001 | |||
| Psychotic illness | 332 (18.6%) | 142 (21.6%) | 101 (14.3%) | |
| Control (age > 25 y) | 295 (16.5%) | 99 (15.1%) | 63 (8.9%) | |
| Putative control | 850 (47.5%) | 323 (49.2%) | 385 (54.4%) | |
| Control combined | 1145 (64%) | 422 (64.2%) | 448 (63.3%) | |
| Putative subthreshold | 268 (15%) | 74 (11.3%) | 146 (20.6%) | |
| Affective psychosis | 33 (1.8%) | 14 (2.1%) | 13 (1.8%) | |
| Unknown | 11 (0.6%) | 5 (0.8%) | 0 | |
| Age in years at last psychiatric assessment | ||||
| Mean (SD) | 21.3 (11.4) | 19.9 (10.0) | 19.0 (6.8) | 0.05692 |
| Median (Range) | 18.0 (2–71) | 17.0 (5–56) | 18.0 (7–61) | |
| IQ-test used (first assessment) | <0.001 | |||
| WPPSI | – | 49 (7.5%) | 32 (4.5%) | |
| WPPSI-R | – | 5 (0.8%) | 18 (2.5%) | |
| WISC-III | – | 153 (23.3%) | 323 (45.6%) | |
| WISC-IV | – | 96 (11.6%) | 100 (14.1%) | |
| WISC-R | – | 24 (3.7%) | 56 (7.9%) | |
| WAIS-III | – | 139 (21.2%) | 49 (6.9%) | |
| WAIS-IV | – | 50 (7.6%) | 9 (1.3%) | |
| WAIS-R | – | 61 (9.3%) | 7 (1.0%) | |
| WASI | – | 80 (12.2%) | 114 (16.1%) | |
| Mean baseline FSIQ (SD) | – | 72.0 (14.3) | 73.3 (13.1) | 0.1048 |
| Mean baseline VIQ (SD) | – | 76.3 (14.5) | 76.9 (14.6) | 0.4236 |
| Mean baseline PIQ (SD) | – | 73.2 (14.9) | 74.0 (13.4) | 0.2741 |
ap value of difference statistic between baseline and longitudinal subsets. T-tests were used for age and IQ-score variables, chi-square tests were used for variables of sex, psychotic illness expression, and IQ-test measures.