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. 2022 May 19;8:266. doi: 10.1038/s41420-022-01036-y

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — A, B Characterization of exosomes isolated from THP-1 macrophages using TEM (A) and NTA (B) analyses. C Western blot analysis of the expression levels of CD63, TS101, and CD9 in exosomes isolated from THP-1 macrophages. D The uptake of PKH67-labeled exosomes by LX-2 cells. Scale bar: 100 μm. E qRT-PCR detection of the NEAT1 expression in exosomes isolated from LPS-treated THP-1 macrophages and non-treated macrophages. **p < 0.01.