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. 2022 May 19;8:266. doi: 10.1038/s41420-022-01036-y

Fig. 2. Exosomes extracted from LPS-treated THP-1 macrophages enhance the activation of HSCs.

Fig. 2

A The NEAT1 expression level was determined by qRT-PCR. B The proliferation of the LX-2 cells was examined by the CCK-8 assay. C The cell cycle of the LX-2 was examined by the flow cytometry. D, E The migration of LX-2 was determined by the scratch assay (D) and the transwell assay (E). F Western blot analysis of the protein levels of collagen I, α-SMA, fibronectin, Sp1, TGF-β1, p-Smad2, Smad2, p-Smad3, and Smad3. *p < 0.05; **p < 0.01; ***p < 0.001.