Fig. 1.

(A) RMSF value for each residue during MD simulations. Flexible domains are highlighted in green rectangles. (B) The structure colored by the RMSF value. Highly flexible domains such as N-term and H8 were removed for clarity. (C) The movement expressed by major PCs. Yellow, green, and blue arrows represent the movement shown by PC1, PC2, and PC3, respectively. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)