Table 1.

Average conservation score for different AT₂R domains.

Domain name	Residue range	Average conservation score
N-terminal	35–44	1.52 ± 0.57
TM1	45–72	1.69 ± 0.83
TM2	78–107	2.28 ± 0.78
TM3	112–148	2.31 ± 0.77
TM4	156–182	2.15 ± 0.69
TM5	203–241	2.12 ± 0.78
TM6	245–285	2.24 ± 0.72
TM7	289–321	2.13 ± 0.81
H8	322–335	1.70 ± 0.73
ICLs	73–77, 149–155, 242–244	0.59 ± 0.86
ECLs	108–112, 183–202, 286–288	2.03 ± 0.82
All loops		1.53 ± 1.08
All TMD		2.12 ± 0.78