TABLE 2.

Chemical analysis of Chinese patent medicines.

Patent drug name	Analytical Methods	Main chemical composition	References
Huaier granules	UHPLC-MS	Proteoglycan,1β-Hydroxyalantolactone, 2-Aminoisobutyric acid, 2-Hydroxybutanoic acid, 2-Isopropyl-3-oxosuccinate, 2′-O-Methyladenosine, 2-Picolinic acid, 3,4-Dihydroxyphenylacetaldehyde, 3-Ethyl-1,2-benzenediol	Pan et al. (2019), Jian et al. (2022)
Ganfule granules	UPLC-Q-TOF-MS	Chlorogenic acid, amygdalin, 3′-deoxysappanone A, 10-O-Methylprotosappanin B, scutellarin, narirutin, hesperidin, hesperetin, nobiletin, 3,3′,4′,5,6,7,8-heptamethoxyflavone, saikosaponin A, Saikogenin C and astragaloside I	Xu et al. (2021)
Fufang Banmao capsule	GC	Cantharidin, ginsenosides Rg1, ginsenosides Rb1, ginsenosides Re, astragaloside A, isofraxidin	Mi et al. (2003)
Jinlong capsule	UPLC	Histidine, serine, arginine, glycine, aspartic acid, glutamate, threonine, alanine, proline, cystine, lysine, tyrosine, methionine, valine, isoleucine, leucine, phenylalanine	LI and Xiao, (2014)
Brucea javanica oil emulsion	HPLC, GC-MS	Brusatol, bruceine D, bruceine H, yadanzioside A, yadanzioside G, javanicoside C and bruceantinoside A, phenol, hexadecanoic acid, octadecanoic acid, 9-Octadecenoic acid (oleic acid), 9E,12Z-Octadecadienoic acid (linoleic acid), 9Z,12Z,15Z-Octadecatrienoic acid	Chen et al. (2009), Zhang et al. (2011), Zhao et al. (2011), Tongtong Wang et al. (2021)
Compound kushen injection	UPLC-MS, HPLC	Adenine, N-methylcytisine, sophorodine, matrine, sophocarpine, oxysophocarpine, oxymatrine, trifolirhizin	Qi et al. (2013), Gao et al. (2018), Shen et al. (2019)

UPLC-MS, ultra-performance liquid chromatography/mass spectrometry; UPLC-Q-TOF-MS, ultra-performance liquid chromatography to quadrupole time-of-flight mass spectrometry; GC, gas chromatography; HPLC, liquid chromatography–mass spectrometry; GC-MS, gas chromatography-mass spectrometry; UHPLC-MS, ultrahigh-pressure liquid chromatography coupled with tandem mass spectrometry.