Figure 1.

(a) Schematic of the cell migration machinery showing the myosin motors and actin bundle that constitute the cytoskeletal network. Adapter proteins (talin) and transmembrane proteins (integrin) form the focal adhesions (FAs) linking the cytoskeletal network to the extracellular matrix/substrate. (b) Motor-clutch model showing the motors and clutches as elastic springs and an inextensible actin bundle with $\pm$ showing the anterograde/retrograde directions. To see this figure in color, go online.