Table 1. Relationship between E-cadherin expression and clinicopathological parameters at diagnosis.

Clinicopathological parameters	E-cadherin Negative ( n=6)	E-cadherin Positive ( n=25)	p value
Age, years (range)	67 (55-82)	67 (46-88)	0.8862
Sex #			1.0000
Male	4	14
Female	2	11
Subtype ♭			0.4655
IgG	4	12
IgA	2	8
Light chain disease	0	5
Light chain #			0.1719
κ chain	1	14
λ chain	5	11
ISS ♭			0.3232
I	0	5
II	5	13
III	1	7
Median Alb, g/dl (range)	2.9 (2.2-3.7)	3.6 (2-4.9)	0.0221 *
Median β2MG, mg/l (range)	3.4 (2-5.5)	4.7 (2-15.3)	0.3067
Median Ca, mg/dl (range)	9.9 (8.1-11.8)	9.6 (7.4-12)	0.5797
Median Cr, mg/dl (range)	1.00 (0.7-1.4)	1.18 (0.5-2.89)	0.4588
Median LDH, U/l (range)	190 (132-295)	186 (99-370)	0.8936
Median Hb, g/dl (range)	8.4 (6.8-10)	10.8 (6.5-17.7)	0.0268 *
Median BM PC, % (range)	66.6 (40-90)	62 (10-90)	0.6893
EMD #			0.0041 *
Present	6	8
Absent	0	17

ISS, International Staging System; Alb, albumin; β2MG, β2 microglobulin; Ca, calcium; Cr, creatinine; LDH, lactate dehydrogenase; Hb, hemoglobin; BM, bone marrow; PC, plasma cell; EMD, extramedullary disease; IgG, immunoglobulin G; IgA, immunoglobulin A.

^* Statistically significant.

^# Fisher’s exact test.

^♭ Chi-square test.