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. 2022 May 19;22:196. doi: 10.1186/s12935-022-02605-y

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 6 — Bionic-based drug delivery to CRC affords immune-cell evasion for efficient NP penetration into CRC microenvironment. A Macrophage based drug delivery. a, Schematics of cancer cell-macrophage hybrid membrane camouflaged IR825/Ir ZGGO@SiO2@CMM nanoplatform for resistant CRC therapy. b TEM images of (i) developed nanomaterials and (ii) element mapping images, c The antitumor effect of combined chemo- and photothermal therapy using hybrid camouflaged system on CT26 cancer in mice. Reproduced from [127] with permission. Copyright (2020) American Chemical Society. B Biomimetic recombinant red blood cell membranes for improved photothermal therapy of colon cancer. a The scheme and procedure for the preparation of IR780 loaded reconstitute RBC membrane nanoparticles (IR780@rRBC NPs). b TEM images of IR780@rRBC NPs. c In vivo cellular uptake and immune-cell escape potential of RBC-stealth NPs on Raw264.7 macrophage cells. Reprinted with permission from [130] under Creative Common Attribution License.4.0. Copyright (2021), Springer Nature

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