Table 2. Intention-to-Treat Primary Outcome Analysis of Association Between Treatment Allocation and BMI, Weight, and Loss of Control Eating at Midtreatment (Month 6), Posttreatment (Month 12), 6-Month Follow-up (Month 18), and 12-Month Follow-up (Month 24) Assessments.
| Interventiona | Estimate (95% credible intervals) | |||||
|---|---|---|---|---|---|---|
| BMIb | Weight, kg | Loss of control eating | ||||
| Comparison with AC | Comparison with BWL | Comparison with AC | Comparison with BWL | Comparison with AC | Comparison with BWL | |
| Difference at the end of treatment | ||||||
| AC | 1 [Reference] | 1.58 (0.72 to 2.45)c | 1 [Reference] | 4.43 (2.08 to 6.81)c | 1 [Reference] | 0.10 (−1.34 to 1.52) |
| ROC | −1.18 (−2.10 to −0.25)c | 0.40 (−0.55 to 1.36) | −3.29 (−5.78 to −0.80)c | 1.45 (−1.16 to 4.00) | −0.27 (−1.84 to 1.29) | −0.18 (−1.78 to 1.42) |
| ROC+ | −1.56 (−2.43 to −0.67)c | 0.03 (−0.88 to 0.93) | −4.79 (−7.21 to −2.39)c | −0.44 (−2.97 to 2.09) | −0.10 (−1.07 to 1.79) | 0.46 (−1.03 to 1.94) |
| BWL | −1.58 (−2.45 to −0.71)c | 1 [Reference] | −4.32 (−6.67 to −1.97)c | 1 [Reference] | 0.36 (−1.54 to 1.33) | 1 [Reference] |
| Difference in rate of change from midtreatment to final follow-up | ||||||
| AC | 1 [Reference] | −0.08 (−0.19 to 0.02) | 1 [Reference] | −0.18 (−0.48 to 0.11) | 1 [Reference] | −0.02 (−0.13 to 0.10) |
| ROC | −0.08 (−0.19 to 0.03) | −0.16 (−0.28 to −0.05)c | −0.22 (−0.53 to 0.09) | −0.32 (−0.63 to −0.01)c | 0.07 (−0.05 to 0.19) | 0.06 (−0.07 to 0.28) |
| ROC+ | 0.05 (−0.06 to 0.16) | −0.03 (−0.14 to 0.08) | 0.14 (−0.07 to 0.50) | −0.07 (−0.37 to 0.24) | 0.01 (−0.10 to 0.13) | −0.001 (−0.12 to 0.11) |
| BWL | 0.08 (−.02 to 0.19) | 1 [Reference] | 0.21 (−0.15 to 0.43) | 1 [Reference] | 0.01 (−0.10 to 0.12) | 1 [Reference] |
Abbreviations: AC, active comparator; BMI, body mass index; BWL, behavioral weight loss; ROC, regulation of cues; ROC+, regulation of cues plus behavioral weight loss.
BMI is calculated as weight in kilograms divided by height in meters squared.
All models include covariates for age, sex, race and ethnicity, physical activity, loss of control eating, type of missing data pattern, and session 1 weight for weight outcome evaluation. Linear mixed effects for time were coded to enable intercept parameters to reflect differences between groups at the end of treatment. Intention-to-treat (ITT) sample model included additional variables to designate missing data group from pattern mixture model. ITT estimates and credible intervals (2.5% to 97.5% intervals reflect a 95% probability of where the true estimate would lie, given the current study data) are estimated from joint imputation models.
Bayesian tail probability P < .05.