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. 2022 Apr 13;109(5):802–811. doi: 10.1016/j.ajhg.2022.03.013

Table 2.

Estimates of SNP heritability on UKBB traits that are significantly different using LDER and LDSC

UKBB ID Phenotype Variable type hLDER2 hLDSC2 p value (different)
1210 snoring binary 0.086 (0.003) 0.058 (0.004) 2.8e−09
1920 mood swings binary 0.097 (0.003) 0.067 (0.004) 1.6e−09
1930 miserableness binary 0.087 (0.003) 0.062 (0.004) 3.1e−07
1950 sensitivity/hurt feelings binary 0.083 (0.003) 0.057 (0.004) 5.7e−09
1970 nervous feelings binary 0.108 (0.003) 0.077 (0.005) 6.2e−08
1980 worrier binary 0.104 (0.003) 0.075 (0.004) 3.8e−08
2000 worry too long after embarrassment binary 0.088 (0.003) 0.061 (0.004) 5.7e−10
2010 suffer from “nerves” binary 0.071 (0.003) 0.052 (0.004) 3.2e−05
2020 loneliness, isolation binary 0.070 (0.003) 0.044 (0.004) 2.9e−08
2030 guilty feelings binary 0.076 (0.003) 0.054 (0.004) 6.8e−07
2040 risk taking binary 0.085 (0.003) 0.064 (0.004) 6.6e−06
2188 long-standing illness, disability, or infirmity binary 0.080 (0.003) 0.058 (0.004) 5.7e−07
2443 diabetes diagnosed by doctor binary 0.207 (0.012) 0.136 (0.011) 8.4e−06
20160 ever smoked binary 0.106 (0.003) 0.077 (0.004) 1.3e−08
6149_100 mouth/teeth dental problems: none of the above binary 0.053 (0.002) 0.038 (0.003) 1.0e−05
6149_6 mouth/teeth dental problems: dentures binary 0.110 (0.004) 0.080 (0.005) 7.3e−07
6150_2 vascular/heart problems diagnosed by doctor: angina binary 0.131 (0.008) 0.083 (0.010) 5.1e−05
30510_irnt creatinine (enzymatic) in urine continuous_irnt 0.057 (0.002) 0.041 (0.002) 3.2e−08
1160 sleep duration ordinal 0.063 (0.002) 0.046 (0.002) 6.9e−09
1200 sleeplessness/insomnia ordinal 0.054 (0.002) 0.040 (0.002) 3.3e−07

The estimates of heritability of binary traits have been transformed to liability scale.