Table 1.

Noteworthy findings in joint analysis of GTEx eQTL and four GWAS traits by different analysis approaches

Complex trait	Analysis approach
	TWAS	VCa	LCb	TWAS + VC	TWAS + LC
Height	116,396	1,674	5,387	1,524	4,701
CAD	2,500	612	1,013	486	762
HDL	4,996	35	652	30	448
LDL	4,238	16	464	14	344
Total	128,130	2,337	7,516	2,054	6,255

For TWAS scanning, the noteworthy genes are identified at a 5% FDR level in each trait-tissue pair; for VC and LC analysis, the noteworthy genes are those with GRCP and GLCP values ≥ 0.50, respectively.

^aVariant-level colocalization analysis.

^bLocus-level colocalization analysis.