. 2022 May 3;7(19):16380–16390. doi: 10.1021/acsomega.2c00225

Table 2. Stern–Volmer Constants (K_SV) for Complexes of Tetrandrine and Its Derivatives Studied Herein with DNA-1, DNA-2, and DNA-3^a.

compound	DNA-1	DNA-2	DNA-3
tetrandrine	7.34 × 10³	^b	^b
BNaphT	1.69 × 10⁴	1.45 × 10⁴	6.76 × 10³
BAqT	1.33 × 10⁵	5.17 × 10⁴	1.53 × 10⁴
BPyrT	4.84 × 10⁴	1.34 × 10⁴	8.26 × 10³
BInT	2.72 × 10⁴	2.32 × 10⁴	1.08 × 10⁴

DNA-1, 5′-GTA AGA TGA TTC-3′ and 5′-GAA TCA TCT TAC-3′; DNA-2, 5′-poly(A)₁₈-3′ and 5′-poly(T)₁₈-3′; DNA-3, 5′-poly(G)₁₈-3′ and 5′-poly(C)₁₈-3′. Complexes were formed in phosphate buffer with 10% DMSO (v/v), pH = 7.2, 0.01 M NaCl, at 25 °C.

Not determined.

Table 2. Stern–Volmer Constants (KSV) for Complexes of Tetrandrine and Its Derivatives Studied Herein with DNA-1, DNA-2, and DNA-3a.

Table 2. Stern–Volmer Constants (K_SV) for Complexes of Tetrandrine and Its Derivatives Studied Herein with DNA-1, DNA-2, and DNA-3^a.