TABLE 3.

Side Effects Raing Scale for Dissociative Anesthetics (SERSDA) results at each timepoint at each visit

SERSDA	Minute	Visit one				Visit two				Visit three				Visit four
		0	30	60	240	0	30	60	240	0	30	60	240	0	30	60	240
Fatigue	Mean	2.9	1	0.7	0.8	1.4	1.6	1.2	1	1.6	1.3	1.2	0.8	1.5	1	1.2	0.7
	SD	0.88	1.15	0.95	0.92	0.84	1.17	1.23	0.82	0.7	1.1	1.1	1.03	1.27	1.25	1.03	0.67
Dizziness	Mean	0.6	0.1	0	0	0.1	0.8	0.3	0	0	0.3	0.1	0	0	0.5	0.2	0
	SD	0.97	0.32	0	0	0.32	1.14	0.95	0	0	0.67	0.32	0	0	0.71	0.63	0
Nausea	Mean	0.2	0.3	0.2	0.1	0.3	0.8	0.6	0	0.1	0.4	0.1	0.4	0.1	0.3	0.3	0.4
	SD	0.42	0.95	0.63	0.32	0.67	1.32	1.07	0	0.32	0.97	0.32	0.97	0.32	0.67	0.67	1.26
Headache	Mean	0.2	0	0	0	0	0.1	0.1	0	0	0	0	0	0	0	0	0
	SD	0.63	0	0	0	0	0.32	0.32	0	0	0	0	0	0	0	0	0
Feeling of unreality	Mean	0.2	0.4	0	0	0	1.3	0.5	0.2	0	0.2	0	0	0	0.2	0.1	0
	SD	0.63	1.27	0	0	0	1.42	1.27	0.63	0	0.42	0	0	0	0.42	0.32	0
Hearing change	Mean	0	0	0	0	0	0.1	0	0.3a	0.1	0	0	0	0	0	0	0
	SD	0	0	0	0	0	0.32	0	0.95	0.32	0	0	0	0	0	0	0
Vision change	Mean	0.4	0.1	0	0	0.1	0.5	0.1	0	0.1	0.1	0	0	0	0.1	0.1	0
	SD	0.7	0.32	0	0	0.32	0.85	0.32	0	0.32	0.32	0	0	0	0.32	0.32	0
Mood change	Mean	0.5	0	0	0	0	0.6	0.4	0	0	0.1	0	0	0.5	0.4	0.1	0.3
	SD	0.85	0	0	0	0	1.26	1.26	0	0	0.32	0	0	1.08	0.7	0.32	0.67
General discomfort	Mean	1.6	0.9	0.6	0.5	1.3	1.1	0.8	0.8	1.2	0.8	0.8	0.8	1.1	0.8	0.8	1.2
	SD	1.51	1.37	1.35	1.08	1.38	1.45	1.32	1.32	1.32	1.32	1.32	1.32	1.45	1.14	1.32	1.62
Hallucination	Mean	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0

Abbreviations: SD, standard deviation; SERSDA, Side Effects Rating Scale for Dissociative Anesthetics.

^aOne subject reported hearing changes at 240 min mark rated as 3 on a scale of 0–4. However, he had chronic ringing in the ears, and this change was unlikely due to the study medication effect.