. 2022 May 4;7(19):16584–16592. doi: 10.1021/acsomega.2c00820

Table 1. F_8–10 Relative Affinity^a.

	F₁–CRM	F₈–CRM	F_9a–CRM	F_9b–CRM	F₁₀–CRM
fentanyl (nM)	17.2 ± 14.8	141.3 ± 63.5	25.9 ± 17.7	69.7 ± 69.2	50.1 ± 26.1
alfentanil (μM)	243	348	203.9	181.4	180.2
acetylfentanyl (nM)	28.59	2090	584	763	6.99
sufentanil (μM)	25.82	>100	20.81	>100	29.04

Fentanyl IC₅₀ expressed as mean ± SEM from all sera in group, n = 6; IC₅₀ for analogues obtained using serum pooled from all samples in each group. Maximum detection limit for alfentanil was 1 mM; detection limit for fentanyl, sufentanil and acetylfentanyl was 100 μM.

Table 1. F8–10 Relative Affinitya.

Table 1. F_8–10 Relative Affinity^a.