Table 2.
Site | Dosimetric constraint/parameter | X1-10 | X1-20 | Eclipse | P (X1-10 vs Eclipse) | P (X1-20 vs Eclipse) | P (X1-10 vs X1-20) |
---|---|---|---|---|---|---|---|
Head and neck | PTV_high D95% 100% | 100.7 | 100.8 | 100.0 | .06 | .06 | .45 |
PTV_intermed D95% 100% | 102.3 | 102.0 | 101.4 | .10 | .06 | .27 | |
PTV_low D95% 100% | 100.5 | 101.0 | 99.8 | .09 | .06 | .25 | |
PTV_high D2%<106% | 104.7 | 105.7 | 104.4 | .35 | .03 | .07 | |
BrainStem Dmax<54 Gy | 17.7 | 21.5 | 28.1 | .003 | .03 | .07 | |
Cochlea_ipsi Dmean<45 Gy | 18.3 | 18.8 | 26.2 | .02 | .02 | .36 | |
Glottis Dmean<25 Gy | 9.4 | 10.4 | 13.1 | .04 | .08 | .02 | |
Lips Dmax<30 Gy | 20.0 | 20.3 | 24.2 | .01 | .004 | .22 | |
Parotid_contra Dmean<26 Gy | 12.3 | 13.6 | 11.1 | .22 | .06 | .01 | |
Pharynx Dmean<45 Gy | 25.1 | 26.5 | 24.7 | .39 | .10 | .09 | |
SpinalCord Dmax<45 Gy | 18.8 | 20.3 | 22.3 | .12 | .31 | .25 | |
Submand_contra Dmean<39 Gy | 20.8 | 19.3 | 23.4 | .09 | .05 | .15 | |
TempLobe_contra Dmax<60 Gy | 9.6 | 11.0 | 7.4 | .15 | .08 | .04 | |
Beam-on Time, min | 11.9 | 8.3 | 2.0 | <.001 | <.001 | <.001 | |
Prostate | PTV_80 D95% 80 Gy | 80.1 | 80.5 | 80.0 | .10 | .06 | .11 |
PTV_80 D2%<106% | 105.7 | 105.3 | 105.1 | .08 | .34 | .24 | |
Bladder V80<15% | 7.5 | 8.2 | 8.0 | .05 | .36 | .10 | |
Bladder V65<50% | 13.9 | 16.4 | 14.2 | .21 | .05 | .03 | |
Femur_L Dmax<50 Gy | 35.5 | 36.3 | 40.3 | .003 | .01 | .23 | |
Femur_R Dmax<50 Gy | 35.9 | 36.4 | 41.0 | .001 | .01 | .31 | |
PenileBulb, Dmean<52.5 Gy | 27.1 | 37.8 | 25.9 | .06 | .01 | .01 | |
Rectum V75<15% | 9.7 | 11.0 | 11.3 | .01 | .38 | .04 | |
Rectum V60<35% | 19.9 | 22.0 | 21.0 | .18 | .29 | .05 | |
Beam-on Time, min | 8.6 | 5.3 | 2.0 | <.001 | <.001 | <.001 | |
Lung SBRT | PTV_50 D95% 50 Gy | 50.8 | 50.5 | 50.0 | .08 | .06 | .10 |
PTV_50 D2%<135% | 124.8 | 121.7 | 123.9 | .37 | .10 | .08 | |
CI<1.2 | 1.0 | 1.0 | 1.0 | .16 | .17 | .44 | |
R50 | 5.7 | 6.5 | 5.2 | .20 | .03 | .02 | |
Chestwall Dmax<52.5 Gy | 43.4 | 41.3 | 41.9 | .31 | .41 | .04 | |
Lungs VS12.4>1000cc | 2967.8 | 2930.3 | 2867.4 | .17 | .26 | .001 | |
Lungs VS11.6>1500cc | 2950.0 | 2909.5 | 2850.1 | .17 | .28 | .001 | |
Lungs V20<10% | 3.2 | 3.7 | 3.2 | .47 | .10 | .002 | |
SpinalCord Dmax<14 Gy | 8.3 | 8.2 | 7.0 | .09 | .09 | .33 | |
Beam-on Time, min | 22.7 | 14.4 | 1.3 | <.001 | <.001 | <.001 |