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. 2022 May 13;8(5):e09394. doi: 10.1016/j.heliyon.2022.e09394

Table 2.

Represent different techniques used for the assessment of liposome parameters.

Liposomes characteristics Characterization technique References
Average particle size Dynamic light scattering (DLS) and microscope technology: Scanning and transmission electron microscopy (SEM/TEM), cryogenic-TEM (Cryo-TEM), and atomic force microscopy (AFM) [179, 180]
Zeta potential/Surface charge Electrophoretic mobility, DLS [181]
Particle shape/morphology TEM, Cryo-TEM, and AFM [182]
Lamellarity Cryo-TEM and ​31P-NMR [182]
Phase behavior X-ray diffraction (XRD), differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA) [183, 184]
Encapsulation efficiency/Drug release Centrifugation, dialysis followed by drug content determination using chromatographic and/or spectrophotometric methods [185, 186]