Fig. 6.

Assessment of Unfolded Protein Response (UPR) Biomarkers. (A-D) UPR response biosensor fold change relative to water control, from at least three independent experiments per exposure group. (A&C) Proteasome specific UPR reporter aip-1p::GFP. (B&D) Endoplasmic reticulum specific UPR reporter hsp-4p::GFP (+ve control: 30 µg/ml Tunicamycin). Top concentrations shown are the maximum concentration not altering adult size or optical density below 80% of control. Error bars: standard error of the mean (SEM), T-test p-values *<0.05, ** <0.005.