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. 2022 May 19;8:12. doi: 10.1186/s41016-022-00278-0

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — A Survival analysis of immune cells and stromal cells and comprehensive survival analysis. It is shown that the tumor microenvironment is associated with survival in LGG patients; the higher the content of stromal cells and immune cells, the worse the prognosis. p < 0.05 represents clinical significance. B The content of stromal cells and immune cells in the tumor microenvironment is independent of the patient’s age and sex and is related to the patient’s tumor grade. Patients presenting with grade III had higher levels of both