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Main characteristics of the studied children
| Mean ± SD | |
|---|---|
| N | 47 |
| Sex (M/F) | 23/24 |
| Age at rhGH onset (year) | 9.8 ± 1.8 |
| Tanner stage (stage 0/stage 1) | 36/11 |
| Mean rhGH dose (µg/kg day) | 70.8 ± 19 |
| Treatment duration (months) | 18.1 ± 7.3 |
| Growth rate before treatment (cm/year) | 4.6 ± 1.0 |
| Growth rate during treatment (cm/year) | 9.1 ± 1.5 |
| Plasma IGF1 at baseline (ng/ml) | 167 ± 80 |
| Mean IGF1during treatment (ng/ml) | 402 ± 123 |
| Delta IGF1 under treatment (ng/ml) | 235 ± 117 |
