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. 2022 May 18;23:467. doi: 10.1186/s12891-022-05438-y

Table 1.

Weighted characteristics of the participants based on serum total alkaline phosphatase quartiles

Serum T-ALP (IU/L) Total Q1(7–50) Q2(51–60) Q3(61–74) Q4(75–326) P value
Age (years) 29.94 ± 6.03 29.99 ± 6.02 30.10 ± 5.93 29.56 ± 6.09 29.59 ± 6.13  < 0.0210
Sex (%)  < 0.0001
 Male 52.95 41.00 53.95 56.58 61.26
 Female 47.05 59.00 46.05 43.42 38.74
Race/ethnicity (%)  < 0.0001
 Non-Hispanic white 35.98 51.59 48.95 46.02 37.75
 Non-Hispanic black 20.31 19.39 18.15 15.30 16.72
 Mexican American 15.64 7.33 10.19 15.46 23.29
 Other race/ethnicity 28.07 21.69 22.70 23.21 22.24
Level of education (%)  < 0.0001
 Less than high school 16.41 9.25 13.54 16.23 21.25
 High school 21.18 17.65 18.70 21.75 24.43
 More than high school 62.41 73.10 67.76 62.02 54.31
Income to poverty ratio 2.30 ± 1.55 2.74 ± 1.59 2.52 ± 1.57 2.36 ± 1.55 2.16 ± 1.51  < 0.0001
Smoking behavior (%) 0.0018
 Every day 11.96 8.91 11.02 12.72 13.41
 Some days 4.22 3.42 4.78 4.70 3.89
 Not at all 9.59 10.27 10.83 10.74 9.61
 Not recorded 74.24 77.40 73.37 71.84 73.09
Alcohol consumption (%) 0.0641
 High alcohol use 7.80 6.46 7.76 7.49 8.87
 None/moderate alcohol use 49.50 50.64 51.84 51.83 47.82
 Not recorded 42.69 42.90 40.40 40.67 43.31
Waist circumference (cm) 95.28 ± 17.05 90.17 ± 15.73 94.01 ± 15.60 96.52 ± 16.74 101.46 ± 18.00  < 0.0001
Blood urea nitrogen (mg/dL) 11.70 ± 3.87 11.72 ± 3.76 12.07 ± 3.71 11.82 ± 3.69 11.65 ± 4.13 0.0146
Serum uric acid (mg/dL) 5.35 ± 1.37 5.03 ± 1.37 5.30 ± 1.36 5.43 ± 1.30 5.66 ± 1.33  < 0.0001
Total protein (g/dL) 7.24 ± 0.44 7.15 ± 0.43 7.19 ± 0.42 7.24 ± 0.44 7.28 ± 0.42  < 0.0001
Total cholesterol (mg/dL) 183.44 ± 37.34 178.50 ± 35.03 181.60 ± 36.61 182.92 ± 35.53 188.48 ± 39.68  < 0.0001
Serum phosphorus (mg/dL) 3.77 ± 0.57 3.82 ± 0.56 3.75 ± 0.54 3.77 ± 0.59 3.76 ± 0.61 0.0061
Serum calcium (mg/dL) 9.41 ± 0.33 9.37 ± 0.32 9.41 ± 0.31 9.43 ± 0.34 9.43 ± 0.33  < 0.0001
Calcium supplementation (mg/d) 378.82 ± 139.01 376.48 ± 114.52 377.29 ± 165.36 375.86 ± 119.25 381.71 ± 143.27 0.6294
Lumbar BMD (g/cm2) 1.05 ± 0.14 1.07 ± 0.14 1.06 ± 0.15 1.04 ± 0.14 1.01 ± 0.14  < 0.0001

Mean ± SD for continuous variables: the P value was calculated by the weighted linear regression model

Percent (%) for categorical variables: the P value was calculated by the weighted chi-square test.

Abbreviation: serum T-ALP serum Total Alkaline Phosphatase, BMD Bone Mineral Density