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. 2022 May 18;23:467. doi: 10.1186/s12891-022-05438-y

Table 2.

The correlation between serum total alkaline phosphatase (IU/L) and lumbar bone mineral density (g/cm2)

Model 1
β (95% CI) P value
Model 2
β (95% CI) P value
Model 3
β (95% CI) P value
total alkaline phosphatase (IU/L) -0.0010 (-0.0012, -0.0008) < 0.000001 -0.0008(-0.0010, -0.0007) < 0.000001 -0.0007(-0.0009, -0.0005) < 0.000001
total alkaline phosphatase categories
 Q1 (7–50) Reference Reference Reference
 Q2 (51–60) -0.0136 (-0.0237, -0.0035) 0.008490 -0.0101(-0.0199, -0.0003) 0.042459 -0.0088(-0.0186, 0.0010) 0.077081
 Q3 (61–74) -0.0337(-0.0436, -0.0238) < 0.000001 -0.0263(-0.0360, -0.0167) < 0.000001 -0.0235(-0.0333, -0.0138) 0.000002
 Q4 (75–326) -0.0603(-0.0704, -0.0502) < 0.000001 -0.0519(-0.0618, -0.0420) < 0.000001 -0.0459(-0.0562, -0.0356) < 0.000001
P for trend  < 0.001  < 0.001  < 0.001

Model 1, no covariates were adjusted

Model 2, age, sex, race/ethnicity were adjusted

Model 3, age, sex, race/ethnicity, education, income to poverty ratio, waist circumference, smoking behavior, alcohol consumption, blood urea nitrogen, serum uric acid, total protein, total cholesterol, serum phosphorus, serum calcium and calcium supplementation were adjusted