Table 3.
Descriptive analysis of patients’ demographics, response to COS and laboratorial ICSI outcomes in repeated cycles.
| Variables | r-hCG Trigger 1st Cycle (n=18) | r-hCG Trigger 2nd Cycle (n=18) | p-value |
|---|---|---|---|
| Female age (years) | 37.44±0.14 | 37.44±0.14 | >0.999 |
| Male age (years) | 38.72±1.65 | 39.11±1.65 | 0.868 |
| Female BMI | 24.72±0.95 | 25.00±0.95 | 0.833 |
| FSH dose (IU) | 2620.59±154.62 | 2841.67±150.26 | 0.305 |
| Length of stimulation (days) | 10.41±1.70 | 10.94±1.75 | 0.377 |
| Length of pituitary suppression (days) | 4.88±1.17 | 4.88±1.17 | >0.999 |
| Number of follicles | 10.00±2.44 | 12.50±2.44 | 0.468 |
| Mature follicular rate (%) | 44.97±26.90 | 35.57±18.26 | 0.242 |
| Estradiol level (pg/mL) | 1520.31±227.97 | 1556.69±322.40 | 0.927 |
| Number of retrieved oocytes | 6.00±1.87 | 9.56±1.87 | 0.178 |
| Oocyte yield (%) | 61.81±2.62 | 72.23±2.62 | 0.190 |
| MII oocyte rate (%) | 62.41±2.63 | 65.54±2.63 | 0.686 |
| MI oocyte rate (%) | 17.00±1.30 | 12.72±1.08 | 0.011 |
| PI oocyte rate (%) | 9.09±0.91 | 10.00±0.79 | 0.450 |
| Fertilization rate (%) | 66.25±2.88 | 67.92±2.38 | 0.655 |
| Blastocyst development rate (%) | 19.75±2.14 | 34.51±1.79 | 0.145 |
Note: Retrospective case-control within-subject analysis performed to compare the response to COS and ICSI outcomes in patients who had two consecutive ICSI cycles triggered with r-hCG only. Values are mean ± standard error, unless otherwise noted. COS – controlled ovarian stimulation, ICSI – intracytoplasmic sperm injection, r-hCG – recombinant human chorionic gonadotropin.