Table 2.

SPR results of 7m, 7u and PF74 binding to monomeric and hexameric CA constructs.

Compounds	KDa (μM)		Koffa(s−1)		Ratiob
	Monomer	Hexamer	Monomer	Hexamer
7m	8.393 ± 1.085	3.218 ± 0.485	0.374 ± 0.095	0.200 ± 0.003	2.608
7u	9.306 ± 1.469	6.647 ± 1.098	0.210 ± 0.080	0.148 ± 0.026	1.400
PF74	3.410 ± 1.310	0.159 ± 0.041	N.D.c	0.018 ± 0.00039	21.446

^aAll values represent the average response from at least 3 replicates. Error bars represent standard deviation

^b.$\text{Ratio}={\text{K}}_{\text{D}}^{\text{Monomer}}/{\text{K}}_{\text{D}}^{\text{Hexamer}}$.

^cN.D.: not determined.