Table 2.
Demographic and clinical characteristics of the TSLP cohort (n=51).
| Characteristics | All (n=51) | Non-Carriers (n=21) | Carriers (n=30) | P-value |
|---|---|---|---|---|
|
| ||||
| n (%) | n(%) | n(%) | ||
| Age (years), Median [IQR] | 16.1 [14.4-17.0] | 16.2 [13.8-17.0] | 16.0 [14.4-16.6] | 0.716 |
| Weight (kg), Median [IQR] | 65.8 [54.1-75.1] | 62.4 [53.8-70.7] | 68.8 [54.4-86.4] | 0.141 |
| Sex | ||||
| M | 28 (54.9%) | 10 (47.6%) | 18 (60.0%) | 0.387 |
| F | 23 (45.1%) | 11 (52.4%) | 12 (40.0%) | |
| Race | ||||
| White | 30 (58.8%) | 11 (52.4%) | 19 (63.3%) | 0.439 |
| Black | 21 (41.2%) | 10 (47.6%) | 11 (36.7%) | |
| Ever diagnosed with asthma | ||||
| Asthma− | 19 (37.3%) | 11 (52.4%) | 8 (26.7%) | 0.064 |
| Asthma+ | 32 (62.7%) | 10 (47.6%) | 22 (73.3%) | |
| Ever diagnosed with AD | ||||
| AD− | 8 (15.7%) | 5 (23.8%) | 3 (10.0%) | 0.186 |
| AD+ | 43 (84.3%) | 16 (76.2%) | 27 (90.0%) | |
| Ever diagnosed with Asthma and AD | ||||
| Asthma− AD− | 2 (3.9%) | 2 (9.5%) | 0 (0.0%) | 0.022 |
| Asthma+ or AD+ | 23 (45.1%) | 12 (57.1%) | 11 (36.7%) | |
| Asthma+ and AD+ | 26 (51.0%) | 7 (33.3%) | 19 (63.3%) | |
*
P-value comparing carriers with TSLP risk genotype and non-carriers using fisher’s exact test for categorical variables and the nonparametric Wilcoxon rank-sum test for continuous variables. Boldface indicates a p-value of less than 0.10.