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. 2022 May 5;9:897264. doi: 10.3389/fmed.2022.897264

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Copyright © 2022 Gutowska, McKinnon, Sarkis, Doster, Bissa, Moles, Stamos, Rahman, Washington-Parks, Davis, Yarchoan, Franchini and Pise-Masison.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Immunophenotypic profiles and surface/activation markers expression in peripheral blood mononuclear cells (PBMCs) isolated from Pom-treated animals. Graphs represent the frequency (%) of different subsets of (A) CD3⁺CD4⁺ cells, (B) CD3⁺CD8⁺CD95⁺ cells, and (C) CD3^–CD8⁺NKG2a⁺ (NK) and CD3⁺CD8⁺NKG2a⁺ (NKT) cells at baseline (B.), day 18, day 24 (last dose of Pom), and day 47 (23 days after treatment). The mean ± standard deviation (error bars) is shown and p-values (*p < 0.05, ^**p < 0.01, and ^***p < 0.001) are given above the columns.