Table 2.
The results of subgroup meta-analysis.
| Subgroups | Number | State V.14.0 | Revman V.5.3 | R V.3.6.3 | ||||
| AUC (95% CI)-ROC | Sensitivity (95% CI) | Specificity (95% CI) | DOR (95% CI) | Result of AUC comparison | AUC | Youden index | ||
| Thoracic surgery | 9 | 0.73 (0.69 to 0.77)* † | 0.73 (0.59 to 0.83) | 0.62 (0.46 to 0.76) | 4 (2 to 10) | 0.35 | ||
| Lateral position | 8 | 0.71 (0.67 to 0.75)‡ | 0.69 (0.55 to 0.81) | 0.62 (0.43 to 0.77) | 4 (2 to 8) | 0.31 | ||
| Supine position | 1 | 0.82 (0.73 to 0.92) | 0.87 (0.85 to 0.89) | 0.66 (0.63 to 0.69) | – | 0.53 | ||
| Thoracoscopy | 3 | High | 0.73 | 0.38 | ||||
| Thoracotomy | 5 | Low | 0.67 | 0.32 | ||||
| Colloid | 8 | 0.76 (0.72 to 0.79） | 0.77 (0.66 to 0.85) | 0.59 (0.42 to 0.74) | 5 (2 to 11) | 0.36 | ||
| Crystalloid | 1 | 0.47 (0.30 to 0.65） | 0.36 | 0.82 | – | 0.18 | ||
| Large bolus | 8 | 0.76 (0.72 to 0.79） | 0.77 (0.66 to 0.85) | 0.59 (0.42 to 0.74) | 5 (2 to 11) | 0.36 | ||
| Small bolus | 1 | 0.47 (0.30 to 0.65） | 0.36 | 0.82 | – | 0.18 | ||
| FloTrac/Vigileo | 6 | High | 0.80* | 0.38 | ||||
| PiCCO | 2 | Low | 0.42 | 0.19 | ||||
| PEEP | 6 | Low | 0.67 | 0.33 | ||||
| Non-PEEP | 2 | High | 0.74 | 0.39 | ||||
| Large TV | 4 | 0.81 (0.77 to 0.84‡) | 0.73 (0.58 to 0.85) | 0.75 (0.58 to 0.86) | 8 (3 to 26) | 0.48 | ||
| Small TV | 5 | 0.67 (0.63 to 0.71) | 0.73 (0.50 to 0.83) | 0.54 (0.32 to 0.74) | 3 (1 to 8) | 0.27 | ||
| Cardiac surgery | 8 | 0.80 (0.77 to 0.83)† | 0.71 (0.65 to 0.77) | 0.76 (0.69 to 0.82) | 8 (5 to 12) | 0.47 | ||
| FloTrac/Vigileo | 3 | Low | 0.73 | 0.46 | ||||
| PiCCO | 5 | High | 0.66 | 0.48 | ||||
| Large bolus | 4 | Low | 0.73 | 0.46 | ||||
| Small bolus | 2 | High | 0.86 | 0.62 | ||||
| Crystalloid | 1 | 0.70 (0.47 to 0.92） | 0.56 | 0.69 | – | 0.25 | ||
| Colloid | 5 | 0.85 (0.81 to 0.88) | 0.79 (0.70 to 0.86) | 0.76 (0.67 to 0.84) | 12 (6 to 25) | 0.55 | ||
| Preoperation | 6 | Low | 0.70 | 0.41 | ||||
| Postoperation | 2 | High | 0.85 | 0.63 | ||||
| Peep | 6 | Low | 0.67 | 0.47 | ||||
| Non-Peep | 2 | High | 0.77 | 0.53 | ||||
| Fluid challenge | 6 | High | 0.73 | 0.52 | ||||
| PLR | 2 | Low | 0.65 | 0.41 | ||||
| ICU after cardiac surgery | 6 | 0.88 (0.86 to 0.92)* | 0.85 (0.60 to 0.96) | 0.85 (0.74 to 0.92) | 32 (9 to 108) | 0.70 | ||
| Fluid challenge | 2 | Low | 0.73 | 0.41 | ||||
| PLR | 4 | High | 0.90 | 0.72 | ||||
*P<0.05 compared with cardiac surgery group.
†P<0.05 compared with ICU group.
‡P<0.05 compared within subgroup.
AUC, area under curve; DOR, diagnostic OR; ICU, intensive critical unit; PEEP, positive end-expiratory pressure; PLR, passive leg raising; ROC, receiver operating characteristic; TV, tidal volume.