TABLE 2.
Multivariable cox regression analysis of all‐cause death and disease recurrence or death of patients with completely resected ES‐NSCLC receiving pACT or no treatment (OBS) after IPTW
| Study group | Outcomes | Treatment | Adjusted a HR | (95% CI) | p |
|---|---|---|---|---|---|
| Overall | All‐cause death | OBS | 1.00 | (Ref.) | |
| pACT | 0.87 | (0.79–0.95) | 0.003 | ||
| Disease recurrence or death | OBS | 1.00 | (Ref.) | ||
| pACT | 0.95 | (0.88–1.03) | 0.191 | ||
| SCC | Death | OBS | 1.00 | (Ref.) | |
| pACT | 0.74 | (0.62–0.88) | 0.001 | ||
| Disease recurrence or death | OBS | 1.00 | (Ref.) | ||
| pACT | 0.74 | (0.63–0.86) | <0.001 | ||
| ADC | Death | OBS | 1.00 | (Ref.) | |
| pACT | 0.92 | (0.83–1.03) | 0.149 | ||
| Disease recurrence or death | OBS | 1.00 | (Ref.) | ||
| pACT | 1.04 | (0.95–1.13) | 0.392 |
Abbreviations: ADC, adenocarcinoma; ES‐NSCLC, early‐stage non–small‐cell lung cancer; HR, hazard ratio; IPTW, inverse probability treatment weighting; OBS, observation; pACT, platinum‐based adjuvant chemotherapy; SCC, squamous cell carcinoma.
a
Adjusted HR was estimated by controlling for baseline characteristics listed in Table 1.