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. 2022 May 18;24(5):e37931. doi: 10.2196/37931

Table 8.

The best multisite phenotyping feature sets and their overall performance characteristics. The multisite phenotypes were derived from Table 7 by selecting components of phenotypes that appeared at multiple sites.

Phenotyping Feature Set Description Sensitivity, specificity
Other Viral Pneumonia OR Acute Respiratory Failure with Hypoxia OR Shortness of Breath OR Abnormal Lung Finding Retrospective phenotype: Diagnoses mentioned in top feature sets at >1 site
  • Site A: 0.79,0.72

  • Site B: 0.88, 0.85

  • Site C: 0.69,0.90b

  • Site D: 0.64,0.58

CRPa AND Ferritin Real-time phenotype: Laboratory tests mentioned in top feature sets at all 4 sites
  • Site A: 0.76,0.85

  • Site B: 0.88, 0.85

  • Site C: 0.42, 0.98

  • Site D: 0.66, 0.55

Remdesivir OR Oxygen (severe) OR Dx of Other Viral Pneumonia Retrospective phenotype: All items mentioned at multiple sites in OR feature sets
  • Site A: 0.74,0.91b

  • Site B: 0.81, 0.94b

  • Site C: 0.60,0.92

  • Site D: 0.61,0.71b

aCRP: C-reactive protein.

bThe top-performing phenotype at each site is italicized.