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. 2022 May 19;2022(5):CD002118. doi: 10.1002/14651858.CD002118.pub6

Brugnon 2010.

Study characteristics
Methods
  • Study type: randomised controlled trial in parallel groups

  • Country: France

Participants
  • Number of participants randomised: 107

  • Age: BS and CS: not stated

  • Number of previous treatments: not stated

  • Infertility duration: not stated

  • Prognosis: good prognosis

  • Inclusion criteria: if more than five oocytes were retrieved and three top‐quality embryos (4 blastomeres, < 20% fragmentation without multinuclear blastomeres) were observed at day two, the couples were included in the study.

  • Exclusion criteria: Not described

Interventions
  • BS group: N = 52

  • CS group (day 3): N = 56

  • Description of the cycles:

    • Sequential media was used in both groups.

    • The freezing method was standard slow freezing method at day 3(FreezeKit, Vitrolife) and at day 5/6 (G‐ FreezeKit Blast, Vitrolife)

Outcomes Cumulative pregnancy rate
Clinical pregnancy rate per embryo transfer
Notes