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. 2022 May 19;17(5):e0268521. doi: 10.1371/journal.pone.0268521

Table 1. Baseline characteristics of 150 women living with HIV, by anal HPV 16 status.

Participant characteristic n (column %) P-value for difference
Total (n = 150)
Anal HPV 16 Positive at baseline (n = 23) Anal HPV 16 Negative at baseline (n = 127)
Age group (Years)
    19–39 6 (26.1) 33 (26.0) 1.00
    40–49 10 (43.5) 55 (43.3)
    50–69 7 (30.4) 39 (30.7)
Place of birth
    Canada 11 (47.8) 24 (18.9) 0.02
    Africa 8 (34.8) 58 (45.7)
    Caribbean 3 (13.0) 40 (31.5)
    Other 1 (4.4) 5 (3.9)
Education completed
    High school or less 19 (82.6) 78 (61.4) 0.05
    College or university 4 (17.4) 49 (38.6)
Smoking
    Never 10 (43.5) 92 (72.4) <0.01
    Past 4 (17.4) 18 (14.2)
    Current 9 (39.1) 17 (13.4)
Injection drug use
    Never 15 (65.2) 120 (94.5) <0.01
    Past 8 (34.8) 5 (3.9)
    Current 0 (0) 2 (1.6)
Lifetime number of vaginal sex partners
    5 or less 11 (47.8) 83 (65.4) 0.11
    More than 5 12 (52.2) 44 (34.7)
Ever having anal sex
    No 16 (69.6) 94 (74.0) 0.07
    Yes 7 (30.4) 33 (26.0)
Lifetime number of anal sex partners
    0 or 1 16 (69.6) 117 (92.1) <0.01
    2 or more 7 (30.4) 10 (7.9)
Past sexual abuse/assault
    No 8 (34.8) 70 (55.1) 0.20
    Yes 15 (65.2) 53 (41.7)
    Don’t know /Prefer not to answer 0 (0) 4 (3.2)
Gonorrhoea (self-report)
    Lifetime 3 (13.0) 9 (7.1) 0.33
    Diagnosis in past 6 mths 0 (0) 0 (0) n/a
Chlamydia ever (self-report)
    Lifetime 3 (13.0) 9 (7.1) 0.33
    Diagnosis in past 6 mths 0 (0) 0 (0) n/a
Anogenital herpes ever (self-report)
    Lifetime 9 (39.1) 14 (11.0) <0.01
    Diagnosis in past 6 mths 5 (21.7) 6 (4.7) 0.01
HPV Vaccination (chart review)
    No 23 (100.0) 121 (95.3) 0.29
    Yes (at least one dose) 0 (0) 6 (4.7)
Hepatitis C infection, current or previous (anti-HCV positive, from chart review) 11 (47.9) 11 (8.7) <0.01
CD4 cell count at baseline (chart review)
    >200 (cells/μL of blood) 19 (82.6) 122 (96.1) 0.01
    ≤200 (cells/μL of blood) 4 (17.4) 5 (3.9)
Nadir CD4 cell count (chart review)
    >200 (cells/μL of blood) 5 (21.7) 77 (60.6), <0.01
    ≤200 (cells/μL of blood) 18 (78.3) 50 (39.4)
HIV viral load (RNA copies/mL of plasma)
    Undetectable (<40) 15 (65.2) 101 (79.5) 0.07
Prevalent Cervical HPV
    Any HPV 20 (87.0) 55 (43.3) <0.01
    High-risk HPV 14 (60.9) 29 (22.8) <0.01
    HPV 16 4 (17.4) 1 (0.8) <0.01

Note. HPV, human papillomavirus; High-risk HPV types include 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 68 [22].