Table 1. The timing of Mdm2^la/la embryonic lethality and rescue by Trp53 deletion.

(A), Viable embryos at the indicated days post conception from inter-mating of Mdm2^la/+ heterozygotes. (B), Live mouse counts from inter-mating of Mdm2^la/+:p53^R/+ heterozygotes. (C), Viable embryos at the indicated days post conception from inter-mating of Mdm2^la/+:p53^R/+ with Mdm2^la/+:p53^R/R mice. n = number of live embryos; (n) = number of dead/resorbed embryos; [n] = Expected Mendelian frequency. Note: p53^R/R mouse numbers were underrepresented due to loss of viability of female embryos in mid-gestation reported previously.

Table 1A, Mdm2la/+ x Mdm2la/+
Genotype	E8.5	E9.5	E10.5	E11.5	Total
Mdm2 la/la	0 (0) [22]	0 (1) [17]	0 (0) [20]	0 (0) [4]	1
Mdm2 la/+	31 (33) [43]	29 (12) [35]	38 (21) [40]	4 (7) [7]	175
Mdm2 +/+	20 (3) [22]	26 (2) [17]	21 (1) [20]	4 (0) [4]	77
Total	87	70	81	15	253
Table 1C, Mdm2la/+:p53R/+ x Mdm2la/la:p53R/R				Table 1B. Mdm2la/+:p53R/+ x Mdm2la/+:p53R/+
Genotype	E9.5	E10.5	Total	Genotype	Live mice
Mdm2la/la:p53R/R	12 (0) [12]	2 (1) [2.5]	15	Mdm2la/la:p53R/R	* 17 [32] [1/4]
Mdm2la/la:p53R/+	2 (7) [12]	0 (1) [2.5]	10	Mdm2la/la:p53R/+	0 [32] [1/4]
Mdm2la/+:p53R/R	13 (0) [12]	2 (2) [2.5]	17	Mdm2la/+:p53R/R	16 [32] [1/4]
Mdm2la/+:p53R/+	12 (2) [12]	2 (0) [2.5]	16	Mdm2la/+:p53R/+	32 [32] [1/4]
Total	48	10	58	Total	65 (128)