Table 7. Primary review findings on fractures.

Study	Outcome	Treatment status	Comparator	Effect estimates (95% CI)
Blum et al. (2015) [45]	Hip fracture	Untreated	Euthyroid	HR 1.02 (0.87–1.19)
	Any fracture			HR 1.11 (0.94–1.30)
	Non-spine fracture			HR 1.13 (0.93–1.38)
	Spine fracture			HR 1.16 (0.66–2.04)
Reyes Domingo et al. (2019) [38]	Fractures; adults (all >65)	Treated	Untreated	HR 1.06 (0.41–2.76)
Yan et al. (2016) [49]	Fractures (any)	Untreated	Euthyroid	RR 1.25 (0.85–1.84)
		Treated		RR 1.22 (0.61–2.47)
Wirth et al. (2014) [44]	Hip fractures	Untreated	Euthyroid	HR 1.10 (0.81–1.50)
	Non-spine fractures			HR 1.11 (0.60–2.05)

HR–Hazard Ratio; RR–Relative Risk.