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. 2022 May 19;17(5):e0267842. doi: 10.1371/journal.pone.0267842

Table 1. Demographic and clinical characteristics of patients.

Characteristics1 Overall data (%)2 NMC p-value Crude OR (95% CI)
No (%) Yes (%)
Demographic characteristics
Mean age ± SD (years) (n = 278) 42.2 ± 12.1 42.8 ± 12.0 40.2 ± 12.4 0.1
Female sex (n = 278) 177 (63.67) 136 (64.2) 42 (62.1) 0.7
Marital status (n = 278) 0.6
Single 89 (32.01) 71 (33.5) 18 (27.3)
Married/cohabitating 137 (49.28) 102 (48.1) 35 (53.0)
Divorced/widower 52 (18.7) 39 (18.4) 13 (19.7)
Education level attained (n = 278) 0.6
None/primary 69 (24.82) 52 (24.5) 17 (25.8)
Secondary 155 (55.76) 121 (57.1) 34 (51.5)
Higher education/university 54 (19.42) 39 (18.4) 15 (22.7)
Clinical characteristics
HIV clinical stage (n = 242) 0.0008
Stage I 1 (0.41) 1 (0.5) 0 (0.0)
Stage II 2 (0.83) 2 (0.9) 0 (0.0)
Stage III 51 (21.07) 48 (22.6) 3 (4.5)
Stage IV 224 (92.6) 161 (75.9) 63 (95.5)
Headaches (n = 269) 174 (64.68) 120 (58.8) 54 (84.4) 0.0001 3.8 (1.7–8.8)
Fever (°C) (n = 269) 179 (66.54) 141 (68.8) 38 (59.4) 0.1
Weight loss (n = 269) 144 (53.53) 107 (52.2) 37 (57.8) 0.4
Consciousness disorder (n = 269) 100 (37.17) 82 (40.0) 18 (28.1) 0.08
Memory impairment (n = 268) 74 (27.61) 59 (28.9) 15 (23.4) 0.3
Neck stiffness (n = 269) 49 (18.22) 33 (15.6) 16 (24.2) 0.1
Vomiting (n = 269) 54 (20.07) 42 (20.5) 12 (18.8) 0.7
Convulsions (n = 269) 23 (8.6) 13 (6.3) 10 (15.6) 0.02 2.7 (1.01–7.1)
Vertigo (n = 269) 32 (11.9) 23 (11.2) 9 (14.1) 0.5
Brudzinski sign (n = 269) 15 (5.58) 8 (3.8) 7 (10.6) 0.05
Physical asthenia (n = 269) 30 (11.1) 23 (11.2) 7 (10.9) 0.9
Kernig sign (n = 269) 14 (5.2) 9 (4.2) 5 (7.6) 0.3
Visual disturbances (n = 269) 8 (2.97) 3 (1.5) 5 (7.8) 0.02 5.6 (1.04–37.5)
Functional Impairment (n = 269) 17 (6.32) 12 (5.9) 5 (7.8) 0.5
Clear CSF appearance (n = 265) 249 (93.9) 200 (94.3) 62 (93.9) 1
Raised CSF opening pressure
(cm H2O) (n = 92)
65 (70.6) 7 (10.6) 17 (65.4) <0.0001
Antiretroviral therapy (ART) (n = 278) 204 (73.4) 153 (72.2) 51 (77.3) 0.4
Poor outcome3 (n = 217) 78 (35.9) 57 (35.4) 21 (37.5) 0.7

1according to available data.

2column per cent calculated for each group.

3Death, status quo, discharge against medical advice, or transfer due to complications.