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. Author manuscript; available in PMC: 2023 Jan 1.
Published in final edited form as: Stat Biopharm Res. 2020 Nov 5;14(2):153–161. doi: 10.1080/19466315.2020.1819403

Table 3:

Summary of simulation results (negative binomial regression) with jump to reference control-based imputation.

Full Data Imputation
Parameter True Mean SD MSE Mean SD SE MSE
n = 200, non-informative censoring
α 1.000 1.0158 0.1382 0.0193 1.0036 0.1732 0.1686 0.0300
β 0 1.609 1.5928 0.1127 0.0130 1.5970 0.1241 0.1245 0.0156
β 1 −0.500 −0.2844 0.1632 0.0266 −0.2724 0.0943 0.0955 0.0090
β 2 0.500 0.5042 0.1664 0.0277 0.5045 0.1859 0.1825 0.0346
n = 400, non-informative censoring
α 1.000 1.0175 0.0965 0.0096 1.0111 0.1227 0.1190 0.0152
β 0 1.609 1.6007 0.0786 0.0062 1.6078 0.0903 0.0867 0.0082
β 1 −0.500 −0.2823 0.1138 0.0130 −0.2736 0.0653 0.0663 0.0043
β 2 0.500 0.4960 0.1097 0.0121 0.4935 0.1276 0.1279 0.0163
n = 200, informative censoring
α 1.000 1.0989 0.1389 0.0291 1.0575 0.1861 0.1848 0.0379
β 0 1.609 1.5934 0.1111 0.0124 1.3821 0.1249 0.1297 0.0631
β 1 −0.500 −0.2064 0.1670 0.0279 −0.2873 0.1047 0.1060 0.0175
β 2 0.500 0.4966 0.1714 0.0294 0.5256 0.1931 0.1957 0.0379
n = 400, informative censoring
α 1.000 1.1082 0.1000 0.0217 1.0736 0.1326 0.1316 0.0230
β 0 1.609 1.6054 0.0807 0.0065 1.4010 0.0957 0.0911 0.0487
β 1 −0.500 −0.2181 0.1157 0.0133 −0.2939 0.0743 0.0738 0.0110
β 2 0.500 0.5023 0.1207 0.0146 0.5302 0.1419 0.1371 0.0211

Mean, sample average of the parameter estimates; SD, sample standard deviation of the parameter estimates; SE, sample average of the standard error estimates; MSE, mean-squared error.