GWAS studies of CVD have identified about 200 loci that contain candidate genes that fit into several risk categories as indicated, although genes do not as yet fit into any known category. GWAS loci for CVD risk factors, including plasma lipid levels (Graham et al., 2021), hypertension (Cabrera et al., 2019), and diabetes (Mahajan et al., 2018), have each identified hundreds of additional, largely non-overlapping loci. [Figure adapted from (Erdmann et al., 2018)].