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. Author manuscript; available in PMC: 2022 May 19.
Published in final edited form as: Nat Chem Biol. 2021 May 10;17(9):954–963. doi: 10.1038/s41589-021-00786-7

Extended Data Fig. 3 |. Sulfopin affects PATu-8988T cell cycle.

Extended Data Fig. 3 |

PATU-8988T cells were treated in triplicates or more for 4 days with either DMSO (0.1%), Sulfopin (2.5 M) or the non-covalent control Sulfopin-AcA (2.5 M). Cell cycle analysis was performed by BRDU and Propidium-Iodide staining, followed by FACS analysis. Sulfopin treatment reduces the % of cells in S-phase and in turn more cells are found in G1, while the non-covalent Sulfopin-AcA doesn’t show this effect. Representative FACS analysis graphs and a quantification of the results SD of two independent experiments are presented (A. n=3; B. n=4). Statistical significance was calculated using one-tailed Student’s t test (** = p < 0.01, *** = p < 0.001).