. Author manuscript; available in PMC: 2023 Jul 1.

Published in final edited form as: J Comp Neurol. 2022 Feb 28;530(10):1729–1738. doi: 10.1002/cne.25310

Table 3.

Sensitivity analysis correlations, after controlling for age, sex, and UPDRS

A. Probabilistic tractography
BDI-II Factor	SCC Tract	Effect Estimate (se)	p-value	Adjusted p-value
Dysphoric mood	L SCC to L mPFC	0.0077 (0.0023)	0.003	0.015
B. ROI-based analysis
BDI-II Factor	ROI	Effect Estimate (se)	p-value	Adjusted p-value
Somatic	External capsule L	0.0123 (0.0057)	0.043	0.414
	Cingulum (cingulate gyrus) R	0.0130 (0.0055)	0.028	0.648
	Superior fronto-occipital fasciculus L	0.0128 (0.0059)	0.040	0.484
	Tapetum R	0.0151 (0.0064)	0.027	0.648
	Tapetum L	0.0131 (0.0050)	0.016	0.757

Multivariable model including age and sex underwent sensitivity analysis by including UPDRS (Unified Parkinson’s Disease Rating Scale) in the model to control for motor function when examining the association of the SCC tracts and/or ROIs with depression symptomatology.