Table 2.

Short characteristic of markers for T lymphocyte immunophenotyping.

Activation markers
CD25	Analysis of T helper (CD4 +) and T cytotoxic (CD8 +) cells with expression of the interleukin's 2 receptor
CD69	Analysis of the early activation stage in T helper and T cytotoxic cells
CD95	Analysis of the early apoptotic stage in T helper and T cytotoxic cells
Intracellular marker
107a	CD107a is a marker of degranulation on T cytotoxic cells and NK cells. CD8+CD107a+ cells could initiate the cytolysis of target cells
Interleukin’s receptor
CD124 (IL-4R)	Analysis of the T helper polarization into Th1 subpopulation
CD212 (IL-12R)	Analysis of the T helper polarization into Th2 subpopulation
Immune synapse receptor expression
CD28	Major costimulation marker, its expression is obligatory for the formation of an immune synapse
Immune checkpoint inhibitor expression
CD279 (PD-1)	Analysis of T helper and T cytotoxic cells with PD-1 expression