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. 2022 May 19;12:8398. doi: 10.1038/s41598-022-12594-7

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Experimental validation on DEGs RASGs by PCBP1 in PBMCs specimens from RA patients. (A) Bar plot showing the RT-qPCR validation results of immune and inflammation related DEGs regulated by PCBP1 in PBMCs from RA. Box plot in the left panel was expression level from RNA-seq in mice, and right panel was RT-qPCR result from RA patients. (****P-value < 0.0001; two-ways ANOVA test). (B) Bar plot showing the RT-qPCR validation results of immune and inflammation related RASEs regulated by PCBP1 in PBMCs from RA. Box plot in the left panel was AS ratio from RNA-seq in mice, and right panel was RT-qPCR result from RA patients. (**P-value < 0.01; ***P-value < 0.001; ****P-value < 0.0001; two-ways ANOVA test).