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. 2022 May 19;12:8433. doi: 10.1038/s41598-022-12423-x

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© This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Neutralization potency of CAP256V2LS versus tyrosine sulfation occupancy. Sulfation fractions from CHO clone 206 were assayed in one experiment for neutralization activity against 4 Env-pseudoviruses, (A) IC₈₀ and (B) relative neutralization potency of each virus, calculated as the IC₈₀ of the 4-SO₃ proteoform divided by the IC₈₀ of the tested fraction.