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. 2022 May 19;12:8433. doi: 10.1038/s41598-022-12423-x

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© This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Lot-to-lot consistency of CAP256V2LS sulfation profile. Five independently produced lots of CAP256V2LS at the 50-l scale included one reference lot, one toxicology lot and three consistency-run lots. (a) % Relative potency values are shown for binding to HIV-1 antigen accordingly to procedures detailed in materials and methods. Reported value %RP for all lots is compared to reference lot. (b) Octet antigen-binding curves.