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. 2022 May 19;12:8467. doi: 10.1038/s41598-022-12095-7

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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The double-lumen catheter used for endometrial sample collection. This type of catheter is commonly used for embryo transfer. The outer hollow catheter (represented in grey) is placed with its distal part just above the internal os of the cervix. Thereafter, the inner catheter (with a smaller diameter, represented in white) can easily pass through the first one, avoiding contacts with the vaginal and cervical mucosae. Once reached the endometrial cavity, endometrial collection of the endometrial fluid can be obtained by gentle traction on the syringe. The box of upper left corner of the figure shows in more details the mechanism of the double-lumen system.