Fig. 2. Comparison of genetic associations with binary phenotype and symbiont state.

Points represent LRT values from two association tests: case-control association by allele frequencies using phenotypes as the dependent variable and continuous association by gene dosage using proportion Durusdinium as the dependent variable. Points (n = 10,803) represent loci shared between the two analyses, excluding those which were filtered to complete continuous association. Point color represents absolute effect size (beta) from symbiont association. Gray lines represent independent LRT value thresholds at p = 0.0001 determined by 10 k permutations. Venn diagram contains counts of these significant loci for phenotype, symbionts and shared between the two. Black line is x = y.