TABLE 2.

Sex difference in gray matter volume of insula subregions

	Males, mean (SE)	Females, mean (SE)	Males vs. females p values
vIa.L	0.633 (0.004)	0.594 (0.004)	3.56 × 10−11
vIa.R	0.706 (0.005)	0.650 (0.005)	8.52 × 10−16
dIa.L	0.689 (0.005)	0.630 (0.005)	2.35 × 10−15
dIa.R	0.739 (0.005)	0.671 (0.005)	1.39 × 10−18
vId/vIg.L	0.622 (0.004)	0.582 (0.004)	1.01 × 10−10
vId/vIg.R	0.654 (0.004)	0.601 (0.005)	2.62 × 10−15
dId.L	0.712 (0.005)	0.654 (0.005)	2.98 × 10−14
dId.R	0.695 (0.005)	0.637 (0.005)	2.54 × 10−14
dIg.L	0.659 (0.005)	0.617 (0.006)	9.99 × 10−8
dIg.R	0.669 (0.005)	0.609 (0.005)	8.40 × 10−14
G.L	0.627 (0.006)	0.572 (0.006)	2.29 × 10−10
G.R	0.591 (0.006)	0.537 (0.006)	4.35 × 10−10

Note: Two‐sample t‐tests were used to examine the sex differences in gray matter volume of insula subregions with age as a nuisance covariate.

Abbreviations: dIa, dorsal agranular insula; dId, dorsal dysgranular insula; dIg, dorsal granular insula; G, hypergranular insula; L, left; R, right; SE, standard error; vIa, ventral agranular insula; vId/vIg, ventral dysgranular and granular insula.